【摘要】 目的探讨保留子宫动脉上行支次全子宫切除对中青年患者卵巢功能的影响。方法选择本院2012年7月~2013年10月收治的因子宫良性病变行子宫切除治疗的患者120例,随机分为两组,对照组患者给予传统的全子宫切除术治疗,观察组患者采用保留子宫动脉上行支次全子宫切除术治疗,观察两组手术时间、术中出血量、术后排气时间、术后住院时间,治疗前、治疗后6个月检测患者卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E2)水平;治疗后随访半年,采用WHO生活质量测定量表简表及国际标准Kuppermann评分评价患者生活质量及更年期症状。结果两组手术时间、术中出血量、术后排气时间、术后住院时间差异无统计学意义(P>0.05);术后6个月观察组FSH、LH明显低于对照组(P<0.05),E2水平明显高于对照组(P<0.05)。术后6个月观察组患者生活质量评分高于对照组(P<0.05),Kuppermann评分显示中重度更年期症状比例低于对照组(P<0.05)。结论保留子宫动脉上行支次全子宫切除对患者卵巢功能的影响较小,利于中青年患者术后生活质量的恢复及更年期症状的减轻或延迟,有较高的临床推广价值。更多还原

【Abstract】 Objective To study the influence of subtotal hysterectomy with uterine artery- ascending branch preservation on Ovarian function of young and middle-age patients. Methods 120 cases treated with hysterectomy due to uterine benign lesions in our hospital from July 2012 to October 2013 were randomly divided into two groups; patients in control group were given traditional hysterectomy treatment, patients in observation group were given subtotal hysterectomy with uterine artery- ascending branch preservation; the operative time, blood loss, postoperative discharge time, postoperative hospital stay time of two groups were observed; before and 6 months after treatment, follicle stimulating hormone(FSH), luteinizing hormone(LH), estradiol(E2) levels were detected; all patients were followed up for six months, life quality and menopausal symptoms was measured by WHO quality of life measurement scale and kuppermann scale. Results The operative time, blood loss, postoperative discharge time, postoperative hospital stay time between two groups was not significantly different(P > 0.05); the FSH, LH of observation group in 6 months after treatment was significantly lower than control group(P < 0.05), E2 levels were significantly higher than control group(P < 0.05). life quality scores of observation group in 6 months after treatment were higher than control group(P < 0.05), Kuppermann scores showed the proportion of moderate and severe menopausal symptoms was lower than the control group(P < 0.05). Conclusion Subtotal hysterectomy with uterine artery- ascending branch preservation has little influence on ovarian function, which will help young patients in life quality recovery and mitigation or delay of menopause symptoms, worthy of clinical application.更多还原