【摘要】 目的:探讨库欣综合征患者的病因分类、各种主要临床表现的出现频率以及实验室检查特点,并评价各种诊断方法的效率。方法:收集1995~2011年广西医科大学第一附属医院住院临床确诊为库欣综合征患者80例的病例资料,对其进行回顾性分析。结果:本组80例中,肾上腺皮质腺瘤最多见,库欣病次之。临床表现方面,高血压出现的频率最高,为76.25%;生化检查中100.00%的患者16:00皮质醇升高,90.92%患者皮质醇节律紊乱;24h尿游离皮质醇检测增高者占90.48%;各种影像学检查中,肾上腺CT具有较明显的优势。结论:临床诊断库欣综合征,应综合各种检查结果以作出正确的判断。更多还原

【Abstract】 Objective:To study the etiologic classification,frequency of various clinical manifestations,laboratorial parameters of Cushing syndrome and evaluate the efficiency of various diagnosis.Methods:The 80 cases of Cushing syndrome were collected from the first affiliatedhospital of Guangxi medical university during 1995~2011.Their clinical data were analyzed retrospectively.Results:In these cases of Cushing syndrome,adrenocortical adenoma was the most common and Cushing disease is a second.In clinical manifestation,the hypertension was overrepresented and it’s expression rate was 76.25% in Cushing syndrome.In biochemical examination,patients with elevated 4PM cortisol level was 100.00%and with cortisol rhythm disorder was 90.92%.24 hour uriuary free cortisol test was 90.48%.In various imaging tests,CT was significant advantages.Conclusion:For the diagnosis of Cushing syndrome,all kinds of results were comprehensively judged.更多还原