【摘要】 目的调查天津市第一中心医院2013年老年慢性阻塞性肺疾病急性加重期(AECOPD)住院患者抗菌药物的用药规律及特点,为临床合理应用抗菌药物提供理论依据。方法对天津市第一中心医院2013年出院主要诊断为慢性阻塞性肺疾病(COPD)伴有急性加重的老年患者的抗菌药物应用情况进行回顾性分析。结果抗菌药共涉及8类34种,合计使用335例次,使用频率较高的主要有β-内酰胺类191例次(57.01%),喹诺酮类78例次(23.28%),抗真菌药41例次(12.24%)。221例使用抗菌药物的患者中,单用一种抗菌药物的为181例(81.90%),两种抗菌药物联合应用的34例(15.38%),三联使用的7例(3.17%)。药敏结果显示多数主要革兰阴性菌和革兰阳性菌对临床常用抗生素均有不同程度耐药。结论天津市第一中心医院老年AECOPD住院患者抗菌药物的应用基本合理,能根据药敏结果及时调整药物。更多还原

【Abstract】 Objective To investigate the medication rules and characteristic of elderly patients with acute exacerbation of chronic obstructive pulmonary disease in 2013 in Tianjin First Central Hospital,so as to provide theoretical evidence for the rational usage of antiviral drugs. Methods Usage situation of antiviral drugs for elderly patients with acute exacerbation of chronic obstructive pulmonary disease in 2013 in Tianjin First Central Hospital was reviewed retrospectively. Results Antiviral drugs involved 8 class 34 species,combined with 335 times. There were 191 cases(57.01%) in β-lactams,78 cases(23.28%) in quinolones,41 cases(12.24%) in antifungal drugs with higher frequency of use. In 221 patients using antiviral drugs,181 cases(81.90%) only used one kinds of antifungal drugs,and 34 cases(15.38%) used two kinds of antifungal drugs. While 7 cases(3.17%) used three kinds of antifungal drugs. The susceptibility tests showed most Gram-negative bacilli and Gram-positive bacilli were more or less drug resistant to common antibiotics. Conclusion In Tianjin First Central Hospital,the utilization of antibiotics is basically reasonable,and the utilization can be adjusted in time according to drug sensitivity.更多还原