【摘要】 目的探讨肿瘤标志物检测联合病理学检查在胃癌诊断中的临床价值。方法对36例胃癌患者(胃癌组)和41例良性胃病患者(良性胃病组)血清中肿瘤标志物检测水平及病理学检查结果等临床资料进行回顾性分析,并与30例健康人(健康对照组)的肿瘤标志物检测水平进行比较,分析3组间的差异。结果胃癌组血清肿瘤标志物检测水平与良性胃病组及健康对照组相比差异有统计学意义(P<0.05)。胃癌患者病理学检查,早期诊断准确率为55.6%,而结合肿瘤标志物检测早期诊断准确率达91.7%,两者差异有统计学意义(P<0.05)。结论采用肿瘤标志物检测联合病理学检查,对胃癌的早期诊断具有较高的敏感度和准确度,临床价值极高,值得推广与应用。更多还原

【Abstract】 Objective To evaluate the diagnosis significans of histopathological observation combined with tumor markers detection in gastric cancer.Methods To retrospectively review the pathological data and serum levels of tumor markers of 36 gastric cancer patients(gastric cancer group)and 41 patients with benign gastric disease(gastric disease group),and to compare with tumor marker detection levels of 30 healthy people(healthy control group)and analyze the differences.Results The serum levels of tumor markers in gastric cancer group were obviously higher than those in healthy control group and gastric disease group(P<0.05).The early diagnosed rate for gastric cancer was 55.6% by histopathological observation,which increased to 91.7% when combined with tumor markers detection.And the difference was significant(P<0.05).Conclusion Histopathological observation combined with tumor markers detection could improve the diagnosis sensitivity and accuracy in gastric cancers.更多还原