【摘要】 目的调查分析6 573例非淋菌性尿道炎(NGU)患者支原体感染情况及对抗菌药物的敏感性,为临床合理用药及流行病学提供依据。方法对6 573例NGU患者进行支原体培养及药敏试验,分别对中国籍患者和外籍患者两组进行比较分析。结果在5 675例中国籍患者中检出支原体感染2 985例(52.6%),其中,解脲支原体(Uu)感染2 312例(40.7%);男性感染率为35.2%,女性感染率为61.4%。898例外籍患者支原体感染440例(49.0%),其中,Uu感染327例(36.4%);男性感染率为32.2%,女性感染率为59.5%。药敏试验结果显示,中国籍患者Uu感染时敏感率依次为米诺环素(MIN)96.7%、多西环素(DOX)96.2%、交沙霉素(JOS)93.7%、克拉霉素(CLA)89.7%;外籍患者依次为MIN(98.9%)、DOX(98.4%)、JOS(95.8%)、CLA(92.1%)。结论中国籍NGU患者支原体感染率略高于外籍患者,感染类型均以Uu为主;女性感染率均明显高于男性;外籍患者对所试药物敏感性均高于中国籍患者,两组患者对MIN、DOX、JOS及CLA均呈现较强的敏感性。更多还原

【Abstract】 Objective To investigate the infection status and drug suscepetibility of mycoplasma from 6 573 patients with nongonococcal urethritis,and to provide the scientific bases for the clinical application of antibiotics.Methods Mycoplasma detection kit was used to detect ureaplasma urealyticum(Uu)and mycoplasma hominis(Mh)and the drug susceptibility.All the patients were divided into two groups:Chinese group and foreigner group.Results Among 5 675 Chinese patients,2 985 patients were infected by mycoplasma(52.6%).The infection rate of Uu was 2 312(40.7%).35.2% patients were male,and 61.4%patients were female.In 898 foreign patients,440 patients were infected by mycoplasma(49.0%).The infection rate of Uu was 327(36.4%).32.2% patients were male,and 59.5% patients were female.In Chinese patients infected by Uu,the susceptibility rates to MIN,DOX,JOS and CLA were 96.7%,96.2%,93.7%,89.7%,respectively.In foreign patients,the susceptibility rates to MIN,DOX,JOS,and CLA were 98.9%,98.4%,95.8%,92.1%.Conclusion The mycoplasma infection rate of Chinese patients is higher than foreign patients.In both groups,Uu infection is the main type.Female patients are more than male patients.The drug sensitivity rate in foreign group is higher than that in Chinese group.mycoplasma are sensitivity to MIN,DOX,JOS.更多还原