【摘要】 目的了解血液感染病原菌分布及耐药情况。方法回顾分析2010年7月至2012年7月该院住院和门诊患者送检的2 162例血培养阳性的标本,采用美国BD公司BACTE9120全自动血培养仪及专用血培养瓶,细菌鉴定采用法国生物梅里埃VITEK32全自动细菌鉴定仪,药敏试验采用K-B法。结果检出致病菌227株,血培养阳性率10.5%,革兰阳性菌156株,占68.7%,革兰阴性菌68株,占30%,真菌3株,占1.3%。葡萄球菌属、链球菌属、肠球菌属耐药率各异,但未发现万古霉素耐药的菌株,革兰阴性杆菌中,各菌属对抗菌药物均有一定的耐药率,但未发现亚胺培南的耐药株。结论血培养病原菌菌谱较广,以革兰阳性菌为主,革兰阴性菌次之,且耐药性情况普遍存在。因此,应及时对血液感染病原菌进行耐药性监测并用于指导临床合理使用抗菌药物。更多还原

【Abstract】 Objective To understand the distribution and drug resistance of pathogenic bacteria about the blood infection.Methods 2 162positive specimens of blood culture of inpatients and outpatients were retrospectively analyzed in our hospital from July 2010to July 2012.The American BD company BACTE 120automatic blood culture apparatus and special blood culture bottle were used in blood culture.Merry Elvis VITEK32automatic bacteria identification instrument was used in bacteria identification.K-B method was applied in the drug sensitive test.Results 227strains of pathogenic bacteria were detected,and the positive rate of blood culture was 10.5%.There were 156strains of gram-positive bacteria accounting for 68.7%,68strains of gram-negative bacteria accounting for 30%and 3strains of fungi accounting for 1.3%.There were different rates of drug resistance about staph, streptococcus and enterococcus,but no vancomycin resistance strain.About gram-negative bacilli,there were some rates of drug resistance.But we did not find imipenem resistance strain.Conclusion Blood culture pathogenic bacteria spectrum is wide,the gram positive bacteria is given priority to,gram negative bacteria takes second place,and the drug resistance is widespread.So we should monitor the blood bacteria resistance in time and guide clinical rational use of antimicrobial agents.更多还原