【摘要】 急性分水岭区脑梗死(Border-zone infarcts,BZI)是指发生于相邻的、较大的2条或2条以上脑动脉供血区交界处的局限性脑梗死。急性BZI约占全部急性脑梗死的10%。根据动脉分布区特点BZI可分为内侧分水岭区脑梗死(Interal border-zone infarcts,IBZI)与皮层分水岭区脑梗死(Cortical border-zone infarcts,CBZI)。BZI的发病机制目前尚不明确。现有的理论认为大脑动脉支配区远端发生低灌注易发生梗死病灶。IBZI主要是血液动力学障碍导致,而CBZI由栓塞及低灌注引发。明确脑梗死的发病机制对有效制定防治措施十分重要。更多还原

【Abstract】 Border-zone infarcts(BZI) are ischemic lesions that occur in characteristic locations at the junction between two main arterial territories.These lesions constitute approximately 10%of all brain infarcts and are well described in the literature.Their pathophysiology has not yet been fully elucidated,but a commonly accepted hypothesis holds that decreased perfusion in the distal regions of the vascular territories leaves them vulnerable to infarction.Two types of BZI are recognized as external(cortical) and internal(subcortical).Internal border zone infarcts(IBZI) are caused mainly by hemodynamic compromise,whereas external border zone infarcts(EBZI) are believed to result from embolism but not always associated with hypoperfusion.It is important to understand the underlying causal mechanisms in selecting most appropriate methods for managing these infarcts.更多还原