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正交实验优选黄连解毒合剂的工艺研究

Technical Study on the Optimization of HuanLian JieDu Mixture by Orthogonal Test

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【作者】 焦正花刘燕珺李文萍

【Author】 JIAO Zhenghua;LIU Yanjun;LI Wenping;Pharmaceutical Preparation Section of Gansu Provincial Hospital of Traditional Chinese Medicine;Jiayuguan Municipality Institute for Drug Control;

【机构】 甘肃省中医院药剂科嘉峪关市药品检验所

【摘要】 目的:优选黄连解毒合剂提取工艺的最佳条件。方法:以干膏、黄芩苷为评价指标,用正交实验法对黄连解毒合剂进行制备工艺的筛选。结果:最佳提取工艺为煎煮2次,每次加水8倍,第1次1小时,第2次0.5小时,醇沉浓度为55%。结论:该优选工艺合理可行。

【Abstract】 Objective: To optimize the best conditions of extraction process of HuanLian JieDu mixture.Methods: The preparation of HuanLian JieDu mixture was screened by orthogonal test by taking the extract yield and baicalin as the evaluating indexes. Results: The best extraction process was as follows: extracting twice, adding water of eight times, extracting for one hour at the first time, half of one hour at the second time, alcohol-precipitation concentration was 55%. Conclusion: The optimized technology is reasonable and feasible.

【基金】 嘉峪关市科技局基金项目(编号2011-38)
  • 【文献出处】 西部中医药 ,Western Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2014年10期
  • 【分类号】TQ461
  • 【被引频次】4
  • 【下载频次】125
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