【摘要】 目的:观察疏肝解郁法联合化疗治疗乳腺癌的临床疗效。方法:将乳腺癌患者56例随机分为2组,治疗组在DA方案化疗基础上加用疏肝解郁代表方柴胡疏肝散加减治疗,对照组采用常规DA方案化疗。3周为1个疗程,治疗2个疗程后以Karnorsky评分法为标准,比较2组患者生活质量、不良反应及预后。结果:Karnorsky评分治疗组高于对照组,差异有统计学意义(P<0.05);化疗引起的不良反应方面治疗组低于对照组,差异有统计学意义(P<0.05);治疗组白细胞、红细胞、血小板减少以及血红蛋白降低的发生率均显著低于对照组,差异具有统计学意义(P<0.05);2组患者治疗后12、24、36个月的生存率比较差异无统计学意义(P>0.05)。结论:疏肝解郁法联合DA方案治疗乳腺癌能提高乳腺癌患者化疗后的生活质量,减轻化疗所致的毒副反应。更多还原

【Abstract】 Objective: To observe therapeutic effects of liver-soothing stagnation-relieving method and chemotherapy in treating breast cancer. Methods: Fifty-six patients were randomized into two groups. The treatment group took modified ChaiHu ShuGan powder on the foundation of DA regimen, and the control group were administered with conventional DA regimen. Three weeks were one course of the treatment, life quality, adverse reaction and the prognosis of the patients in both groups were compared after two courses of the treatment according to Karnorsky scaling method. Results: Karnorsky scale of the treatment group was higher than that of the control group,the difference showed statistical meaning(P <0.05); the treatment group was lower than the control group in chemotherapy-induced adverse reaction, the difference demonstrated statistical meaning(P<0.05); it was lower than the control group obviously in the incidences of white blood cells, red blood cells, platelet and hemoglobin, the difference showed statistical meaning(P<0.05); the difference had statistical meaning in the comparison of 12, 24 and36 months survival rate after treating(P>0.05). Conclusion: Liver-soothing stagnation-relieving method and DA regimen in treating breast cancer could raise life quality of the patients after breast cancer and alleviate chemotherapy-induced toxicity.更多还原