【摘要】 目的了解周口市无偿献血者丙型肝炎病毒抗体(抗HCV)阳性情况。方法采用酶联免疫检测法,对周口市2007—2012年采集的200 950份无偿献血者样本进行抗HCV双试剂检测,并对结果进行统计分析。结果2007—2012年无偿献血者抗HCV总阳性率为0.21%(416/200 950),不同性别、年龄、学历献血者抗HCV阳性率比较,差异均有统计学意义(χ2分别为24.01、142.31、45.8,均P<0.01),其中女性抗HCV阳性率(0.27%,205/75 658)高于男性(0.17%,211/125 292);21~30岁组献血者阳性率(0.06%,38/63 719)最低,>40岁组阳性率(0.33%,162/48 871)最高;学历越低,抗HCV阳性率越高,初中学历人群阳性率为0.26%(107/41 154)。2007—2012年,献血者抗HCV阳性率逐年下降(χ2=14.576,P<0.05)。结论该市无偿献血者中抗HCV阳性率较低,人群阳性率分布有差异。更多还原

【Abstract】 Objective To investigate the prevalence of anti-HCV positive among volunteer blood donors in Zhoukou city.Methods A total of 200 950 blood specimens from voluntary blood donors in Zhoukou from2007 to 2012 were detected for anti-HCV by double-antibody sandwich enzyme-linked immunosorbent assay,results were analyzed.Results The total positive rate of anti-HCV was 0.21%(416/200 950),there were significant difference in positive rates of anti-HCV among populations of different genders,ages and educational background(χ2=24.01,142.31,45.8,respectively,all P<0.01),the positive rate of anti-HCV in female was higher than that of male([0.27%,205/75 658]vs[0.17%,211/125 292]);the positive rate of anti-HCV was the lowest in donors aged21-30 years(0.06%,38/63 719),and highest in donors aged>40 years(0.33%,162/48 871);the lower donors received education,the higher positive rate of anti-HCV they had,the positive rate of anti-HCV in donors with junior high school education was 0.26%(107/41 154).The positive rate of anti-HCV in blood donors decreased gradually from2007 to 2012(χ2=14.576,P<0.05).Conclusion The positive rate of anti-HCV is low in voluntary blood donors in Zhoukou and is significantly different among different populations.更多还原