【摘要】 目的了解某院临床分离的常见非发酵菌的分布及耐药情况。方法回顾性分析该院2012年1月1日—12月31日临床送检标本分离的非发酵菌的资料。结果 2012年共收集4 559份标本,分离非发酵菌427株(9.37%),其中铜绿假单胞菌、鲍曼不动杆菌和嗜麦芽窄食单胞菌共405株,占94.85%(405/427)。上述3种常见非发酵菌主要分离于痰标本(75.89%~78.79%),耐药性都较高。铜绿假单胞菌对阿米卡星、美罗培南、多粘菌素B的耐药率较低,分别为14.54%、11.89%、14.98%;鲍曼不动杆菌耐药率低的抗菌药物为亚胺培南、美罗培南、多粘菌素B,耐药率分别为6.25%、6.25%、8.04%;嗜麦芽窄食单胞菌对复方磺胺甲口恶唑的耐药率仅为3.03%,对多粘菌素B的耐药率仅为13.64%。结论该院非发酵菌主要分离自下呼吸道标本,且耐药性较高,需要根据药敏结果合理选药治疗并防止感染传播。更多还原

【Abstract】 Objective To realize the clinical distribution and antimicrobial resistance of common non-fermentative bacteria from a hospital.Methods Data of non-fermentative bacteria isolated between January 1,2012 and December 31,2012 were analyzed retrospectively.Results A total of 427(9.37%)isolates of non-fermentative bacteria were isolated from4 559 specimens,405(94.85%,405/427)isolates of which were Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia,these strains were mainly isolated from sputum specimens(75.89%-78.79%)and with high antimicrobial resistance,but the resistant rate of Pseudomonas aeruginosa to amikacin,meropenem,and polymyxin B was low(14.54%,11.89%,and 14.98% respectively),the resistant rate of Acinetobacter baumannii to amikacin,meropenem,and polymyxin B was low(6.25%,6.25%,and 8.04% respectively),the resistant rate of Stenotrophomonas maltophilia to compound sulfamethoxazole and polymyxin B was low(3.03%and 13.64%respectively).Conclusion Non-fermentative bacteria in this hospital are mainly isolated from lower respiratory tract specimens,and antimicrobial resistance is high,antimicrobial agents should be used according to antimicrobial susceptibility testing result,and spread of infection should be prevented.更多还原