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肝癌肝切除术后感染并发症相关危险因素分析
Analysis of risk factors of postoperative infection complications after hepatectomy for hepatocellular carcinoma
【摘要】 目的探讨肝癌肝切除术后感染并发症相关危险因素。方法对本院近6年来行肝切除术的217例肝癌患者的临床资料进行回顾性分析,对可能引起感染并发症的因素进行统计学分析。结果 217例肝癌肝切除病例根据术后是否发生感染并发症分为感染组(n=33)与非感染组(n=184)。33例中,手术部位感染15例(占45.45%)、肝脏周围感染4例(占12.12%)、远处部位感染14例(占42.42%);术后死亡3例(占1.38%)。多因素Logistic逐步回归分析显示年龄(P=0.006,OR=2.564)、糖尿病史(P=0.02,OR=1.996)、手术时间(P=0.005,OR=2.237)及胆漏发生率(P<0.001,OR=7.325)是肝切除术后感染并发症的独立危险因素。结论年龄、糖尿病史、手术时间及胆漏发生率是影响肝癌患者肝切除术后感染并发症发生的独立危险因素。
【Abstract】 Objective To explore the risk factors of postoperative infection complications after hepatectomy in hepatocellular carcinoma patients. Methods The clinical data of 217 hepatocellular carcinoma patients after hepatectomy from Apr. 2006 to Oct. 2012 were retrospectively analyzed and the risk factors that may cause infection complications were explored with statistical methods. Results All 217 cases were divided into infection group(n=33) and non-infection group(n=184). In our study, the incidence of postoperative infection was 15.21%(33/217), and the surgical site infection in15 cases(45.45%), the liver surface infection in 4 cases(12.12%), the remotesite infection in 14 cases(42.42%). The surgical mortality was 1.38%(3/217). Multiple Logistic regression analysis showed the independent risk factors for postoperative infectious complications after hepatectomy included age(P=0.006, OR=2.564), history of diabetes(P=0.02, OR=1.996), operative time(P=0.005,OR=2.237) and bile leakage rate(P<0.001, OR=7.325). Conclusion Age, history of diabetes, operative time and bile leakage are the independent risk factors for postoperative infectious complications after hepatectomy.
【Key words】 carcinoma,hepatocellular; hepatectomy; infection; risk factors;
- 【文献出处】 肝胆胰外科杂志 ,Journal of Hepatopancreatobiliary Surgery , 编辑部邮箱 ,2014年03期
- 【分类号】R735.7
- 【被引频次】29
- 【下载频次】200