【摘要】 纤溶酶原激活物抑制剂-1是纤维蛋白溶解系统成员纤溶酶原激活剂,体内纤溶酶原激活物抑制剂-1水平和活性的变化在血栓性疾病以及肿瘤的发生、发展过程中发挥着极其重要的作用,但目前研究报道的纤溶酶原激活物抑制剂-1小分子抑制剂还处于前期开发阶段,未见有相关药物上市。文章综述了近年来纤溶酶原激活物抑制剂-1的研究进展。更多还原

【Abstract】 Plasminogen activator inhibitor-1 is the fibrinolytic system member plasminogen activator,which plays a important role in thrombotic disease and the occurrence,expansion of tumor.While the research reports of plasminogen activator inhibitor-1 small molecule inhibitors is still in the early stages,there is no related drugs to market.In the paper,we summarizes the research progress of plasminogen activator inhibitor-1.更多还原