【摘要】 目的比较糖尿病(DM)患者与非DM患者支架植入术后支架边缘血管形态学情况观察结果。方法选择常规冠状动脉造影指导下行介入治疗后的100例患者进行血管内超声检查,其中DM患者35例,非DM患者65例。结果在远端参考血管段,DM患者与非DM患者相比,血管外弹力膜面积[(13.40±5.34)mm2vs(13.44±5.37)mm2]差异无统计学意义(P=0.97),DM患者远端参考血管管腔面积小于非DM患者[(7.04±2.47)mm2vs(8.67±3.76)mm2],差异有统计学意义(P<0.05),斑块负荷大于非DM患者[(43±18)%vs(32±23)%],差异有统计学意义(P<0.05);支架内远端支架面积小于非DM患者[(7.61±2.43)mm2vs(8.55±2.48)mm2,P=0.05];斑块负荷大于非DM患者[(46±7)%vs(36±15)%],差异有统计学意义(P<0.05)。支架远端斑块负荷>50%的比例,DM患者高于非DM患者(36.8%vs 22.2%),但差异无统计学意义。结论常规造影指导的DM患者介入治疗后,支架远端管腔面积小,斑块负荷重,这可能是DM患者支架远端再狭窄率高于非DM患者的原因。更多还原

【Abstract】 Objective To compare the morphology of the vessels between diabetic mellitus( DM) patients and non-DM patients after percutaneous coronary intervention( PCI).Methods One hundred patients( 35 DM and 65 non-DM) who underwent intravascular ultrasound( IVUS) examination after angiographic-guided PCI were enrolled.Results At the distal reference segments,there was no significant difference between DM patients and non-DM patients in external elastic membrane area [( 13.40 ± 5.34) mm2vs( 13.44 ± 5.37) mm2,P = 0.97],but significantly smaller MLA was observed in DM patients than that of non-DM patients [( 7.04 ± 2.47) mm2vs( 8.67 ± 3.76) mm2,P <0.05],with significantly larger plaque burden( PB) in DM patients than that in non-DM patients [( 43 ± 18) % vs( 32 ± 23) %,P < 0.05].At distal part of the in-stent segments,smaller MSA [( 7.61 ± 2.43) mm2vs( 8.55 ± 2.48) mm2,P = 0.05]and larger PB [( 46 ± 7) % vs( 36 ± 15) %,P < 0.05]were observed in DM patients than non-DM patients.At distal stent margins,the proportion of patients with PB over 50% was higher in DM patients than non-DM patients,but with no significant difference( 36.8% vs 22.2%,P > 0.05).Conclusion After angiographic-guided PCI,smaller MLA and bigger PB at distal stent margins may relate to the high risk of distal edge restenosis in DM patients.更多还原