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阑尾杯状细胞类癌的病理特征与治疗

The pathological features and treatment of goblet cell carcinoid of appendix

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【作者】 王卓才冯晓冬黄小让陈炳旭

【Author】 WANG Zhuo-cai;FENG Xiao-dong;HUANG Xiao-rang;CHEN Bing-xu;Department of Pathology,General Hospital of Guangzhou Military Command of PLA;

【机构】 广州军区广州总医院病理科广州金域医学检验中心病理部广州军区广州总医院综合科

【摘要】 目的探讨阑尾杯状细胞类癌(GCC)的病理特征和治疗。方法分析8例阑尾GCC的病理特征及治疗特点。结果本组阑尾GCC患者年龄(53.5±12.3)岁,男5例,女3例,常表现为阑尾炎,少数无症状或右下腹肿块。多因阑尾炎或其他手术偶然诊断。肿瘤浸润阑尾肌层或浆膜层不形成肿块。治疗首选手术,依据肿瘤大小和浸润转移范围选择阑尾切除和(或)半结肠切除术,>50岁女性主张全子宫双侧输卵管卵巢一并切除。随访26~79个月,平均(53.6±2.3)个月,未见复发转移。结论阑尾GCC罕见,不形成明显肿块,临床无特异性特征。治疗依据肿瘤部位、大小、浸润和转移范围决定手术和(或)化疗方案。预后大多良好。

【Abstract】 Objective To investigate the pathological features and treatment of goblet cell carcinoid( GCC) of appendix. Methods Pathological diagnosis and treatment of 8 cases of GCC of appendix were analyzed. Results The mean age of patients with appendix GCC was( 53. 5 ± 12. 3) years,including 5 male cases and 3 female cases. Appendicitis like symptoms was most common observed,and a few with no symptom or right lower quadrant mass. Accidental diagnosis was usually made in appendicitis or other surgery. Myometrial or serosal invasion in appendix was observed with no lumps. Surgical treatment was the primary choice; and based on tumor size and metastasis range,selected appendectomy and /or right hemicolectomy were selected,while bilateral salpingo- oophorectomy was also advocated in females over 50 years old. During the follow- up of( 53. 6 ± 2. 3) months,no recurrence was reported. Conclusion Appendix GCC is rare with occult symptoms and no significant mass. Treatment is selected based on tumor location,size,invasion and metastasis range,with fair prognosis.

  • 【文献出处】 广东医学 ,Guangdong Medical Journal , 编辑部邮箱 ,2014年04期
  • 【分类号】R735.36
  • 【被引频次】2
  • 【下载频次】83
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