Nitrotyrosine is a product of of tyrosine nitration mediated by peroxynitrite anion and nitrogen dioxide, which is well acknowledged as a significant factor in diabetes mellitus(DM). It is regarded as a marker of oxidative stress(OS) and a risk predictor of chronic complications of DM to assist clinical diagnosis and therapy. Present researches have found that NT has its own pathological activities, such as causing damages of protein, mitochondria and cell. Thus, in this paper, generation pathology effect o...
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