【摘要】 目的 探讨血清胱抑素C检测对老年慢性肾衰竭患者的临床意义。方法 98例老年慢性肾衰竭患者为观察组,同期进行健康体检的36例老年人为对照组,两组均进行血清胱抑素C、肌酐和尿素氮检测,并比较分析。结果 观察组血清胱抑素C、肌酐和尿素氨水平均显著高于对照组(P<0.01)。观察组中Ⅰ期、Ⅱ期、Ⅲ期和Ⅳ期患者血清胱抑素C、肌酐和尿素氮水平比较,差异均有统计学意义(Ⅰ期<Ⅱ期<Ⅲ期<Ⅳ期,P<0.01)。在Ⅰ期患者中,胱抑素C检测的阳性率明显高于肌酐和尿素氮(P<0.05)。结论 血清胱抑素C可作为早期诊断老年慢性肾衰竭的敏感指标,并对判断病情严重程度有重要价值。更多还原

【Abstract】 Objective To investigate the clinical significance of serum cystatin C(Cys-C)testing in old patients with chronic renal failure(CRF).Methods 98 patients with CRF were observation group.36 healthy old people were served as the control.The levels of serum Cys-C,Scr,and BUN of the 2 groups were tested and compared.Results The levels of serum Cys-C,Scr,and BUN of the observation group were significantly higher than those of the control(P<0.01).There were significantly differences among period Ⅰ,period Ⅱ,period Ⅲ,and period IV patients in the observation group about the levels of Cys-C,Scr,and BUN(P<0.01).Positive rate of Cys-C testing in period I group was significantly higher than those of Scr and BUN(P<0.05).Conclusion Serum Cys-C could be a sensitive indicator for early diagnosis in old patients with CRF,and it had an important value to evaluate the severity of the disease.更多还原