【摘要】 目的探索不同认知功能孤独症谱系障碍(autism spectrum disorder,ASD)儿童在心理教育评估量表第3版(PEP-3)中反应特征,为临床诊断和康复提供可循依据。方法以智力测试结果为界定标准,选择低功能ASD(LFA)、高功能ASD(HFA)和正常对照组儿童各26例,各组性别、年龄相匹配各组男23例、女3例,年龄在2~5岁间,平均年龄分别为(40.92±9.60)、(40.07±7.60)、(40.12±9.31)月,采用香港版PEP-3量表的功能发展量表对其进行测评分析。结果 LFA儿童在PEP-3所有功能领域的原积分和发展年龄均明显落后于对照组(P<0.001),HFA组的认知、大肌肉测验的原积分和发展年龄均低于对照组(P<0.05);LFA组的认知、语言表达、语言理解、模仿测验的原积分和发展年龄均明显低于HFA组(P<0.001),小肌肉测验的原积分和发展年龄均低于HFA组(P<0.05)。LFA组在合成项沟通和体能的功能商数表现为"低-高"趋势(51.68±14.34VS 75.08±9.00,P<0.001),HFA组则呈现"均衡"现象(91.40±12.93VS87.02±11.66,P=0.205)。结论不同认知功能ASD儿童PEP-3评价结果反映了不同模式,可作为辅助诊断和教育干预的参考。更多还原

【Abstract】 Objective To explore the developmental profile of children with autism spectrum disorder(ASD)on PEP-3. Methods A total of 52children with ASD who were divided into two groups according their intelligence level,lowfunction autism(LFA)and high-functioning autism(HFA),and 26aged-matched typically children were evaluated by PEP-3(each group included 23boys and 3girls,aged 2~5years old). Results LFA children exhibited a greater developmental delay in all subtests on PEP-3as compared with typically children(P<0.001).The scores and developmental ages on the cognitive verbal/preverbal(CVP)and gross motor(GM)subtests were lower in HFA group than TD group(P<0.05). LFA group significantly scored lower than HFA group on CVP,expressive language(EL),receptive language(RL),fine motor(FM)and visual motor imitation(VMI)subtests(P<0.05).For the communication composite and motor composite,children with LFA exhibited "low-high" trend(51.68±14.34VSs 75.08±9.00,P<0.001),while HFA group presented "balanced" phenomenon(91.40±12.93VS 87.02±11.66,P=0.205). Conclusion Children with ASD of different intelligence level exhibites differently on PEP-3.更多还原