Objective To investigate the dynamic changes of matrix metalloproteinase-9(MMP-9) level in tear fluid within 12 months after laser in situ keratomileusis(LASIK). Methods Twenty-two myopic patients undergoing uneventful LASIK were enrolled in this study. Tear fluid samples were collected from the patients for measurements of MMP-9 level using Western blotting preoperatively, at 7 and 14 days, and at 1, 2, 3, 6, and 12 months after the surgery. Results MMP-9 concentrations in the tear fluid of post-LASIK pati...
【基金】
Supported by grants from the Science and Technology Council of Guizhou Province([2011]025,[2008]118)~~
【更新日期】
2014-08-29
【分类号】
R779.63
【正文快照】
INTRODUCTIONLaser in situ keratomileusis(LASIK)is associatedwith such complications as flap melt,epithelialingrowth,myopia regression,and devastating ectasiadue to postoperative inflammation and wound healing.In human corneas with post-LASIK ectasia that