Objective To evaluate the short-term clinical efficacy and safety of laparoscopic Roux-en-Y gastric bypass(LRYGB) in obese patients with type 2 diabetes mellitus(T2DM).Methods Twelve obese T2DM patients undergoing LRYGB from May 2010 to August 2013 were recruited in this study.They were 4males and 8 females,with a mean age of 43.8 ± 10.6 years,a mean duration of T2DM for 8.3 ± 3.9 years,a body mass index of 31.3 ± 5.6 kg / m2,fasting plasma glucose of 9.4 ±1.9 mmol/L,and HbA1c of(8.4 ±1.6) % before surgery....