胰岛素在急性缺血性脑卒中伴糖尿病治疗中应用

【摘要】 目的探讨和分析胰岛素对急性缺血性脑卒中合并糖尿病患者神经功能产生的影响。方法选取东莞市长安医院2012年10月~2013年9月急性缺血性脑卒中合并糖尿病病例共188例,随机分实验组(n=106)和对照组(n=82),对照组常规治疗,实验组在对照组治疗基础上加用胰岛素进行治疗,对比2组患者临床疗效、神经功能评分、Barthe指数(巴氏指数)。结果实验组痊愈54例,显效35例,有效14例,总有效率为97.17%,对照组痊愈26例,显效27例,有效22例,总有效率为91.46%,实验组疗效显著优于对照组(P<0.05),且实验组治疗第15 d、第30 d NIHSS评分和Barthe指数改善均优于对照组(P<0.01)。结论对急性缺血性脑卒中合并糖尿病患者早期使用胰岛素控制血糖,可使患者获益,血糖控制不佳急性脑卒中患者存在更大的病情进展可能。更多还原

【Abstract】 Objective To investigate and analyze the insulin on acute ischemic stroke neurological function in patients with diabetes mellitus impact. Methods Select I Dongguan Changan hospital to hospital from October 2012 to September 2013 with acute ischemic stroke of 188 diabetic patients were randomly divided into experimental group(n=106) and control group(n=82), the conventional treatment group the experimental group were based on the use of insulin therapy treatment, clinical efficacy compared two groups of patients with neurological changes in ratings, Barthe Index(Barthel Index). Results 54 cases were cured, 35 cases markedly effective in 14 cases, total effective rate was 97.17% in the control group cured 16 cases, 27 cases markedly effective in 22 cases, total effective rate was 86.59% in the experimental group was significantly better than in the control group(P<0.05), and 15 days of treatment in the experimental group, the first 30 days NIHSS score and improve Barthe index than the control group(P<0.01). Conclusion Acute ischemic stroke patients with early diabetes use insulin to control blood sugar, patients can benefit, there is a greater glycemic control may be poor progression in patients with acute stroke.更多还原