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前列腺癌CT多期增强特征与血清PSA的相关性研究
Characteristics of Multi-phase Enhanced CT of Prostate Cancer and Its Correlation of Serum PSA
【摘要】 目的探讨前列腺癌CT多期增强特征与血清PSA的相关性,以分析其诊断前列腺癌的价值。方法选择97例前列腺癌患者进行CT检查,观察其CT多期增强特征,同时检测其血清前列腺组织特异性抗原PSA的水平,并比较患者与良性前列腺患增生患者PSA水平的差异,分析前列腺癌CT多期增强特征与血清PSA的相关性。结果经CT检查发现,前列腺癌患者的动态增强开始时间为(37±12)s,早于对照组的(49±14)s;前列腺癌患者的最大信号强度为(146.45±75.21)%,早期强化率为(124.34±84.95)%,两者均高于对照组的(109.11±60.01)%和(75.33±42.46)%。两组患者这三个参数之间的差异均具有统计学意义(P<0.05)。前列腺癌组患者的血清PSA水平为(61.01±45.23)ng/ml,显著高于对照组患者的(9.12±8.67)ng/ml,差异具有统计学意义(P<0.05)。结论前列腺癌CT多期增强特征与血清PSA的水平呈明显的相关性,这可为前列腺癌的诊断、治疗提供新思路。
【Abstract】 Objective Investigate the characteristics of multi- phase enhanced CT of prostate cancer and its correlation with serum PSA, in order to analyze the diagnostic value of prostate cancer. Methods A total of 97 patients with prostate cancer underwent CT multi-phase scan, simultaneous detection of prostate-specific antigen in serum PSA levels and compared with patients with benign prostatic hyperplasia patients suffering from differences in PSA levels. prostate cancer CT analysis enhanced features multiphase correlation with serum PSA. Results The CT dynamic contrast-enhanced start time of prostate cancer was(37±12)s, earlier than the control group(49±14) s; maximum signal strength of prostate cancer was(146.45±75.21)%, early strengthening was(124.34±84.95)%, both higher than the(109.11±60.01)% and(75.33±42.46)%, there were statistically significant(P<0.05). Prostate cancer patients with serum PSA level was(61.01±45.23) ng/ml, was significantly higher in patients(9.12±8.67) ng/ml, a statistically significant difference(P<0.05). Conclusion The multi-phase enhanced CT prostate cancer characteristics and serum PSA levels were significantly correlated, which provided new ideas for the future diagnosis and treatment of prostate cancer.
【Key words】 Prostate Cancer; CT; Prostate Specific Antigen; Prostatic Hyperplasia;
- 【文献出处】 中国CT和MRI杂志 ,Chinese Journal of CT and MRI , 编辑部邮箱 ,2014年08期
- 【分类号】R737.25;R730.44
- 【被引频次】2
- 【下载频次】98