【摘要】 目的研究国产SWS-4000型血透机的治疗效果、安全性、稳定性。方法采用前瞻、开放、随机对照研究方法研究国产SWS-4000型血透机,以进口金宝AK-200型血透机为对照;以住院慢性肾功能衰竭新入透析患者为研究对象,在为期2年的观察期内,SWS-4000型血透机纳入507例(8 094人次),AK-200血透机纳入593例(8 150人次);观察近期、长期透析效果、透析并发症、机器配液等指标。结果治疗过程中不同血透机型患者低血压、高血压、胸闷、心悸、恶心、肌肉痉挛等发生率差异无统计学意义(P>0.05);SWS-4000型血透机误超的离散度较大,水路报警较多,透析液钠离子浓度较高(P<0.05),但可通过下调机器的电导设定值来纠正;采用SWS-4000型血透机单次透析后KT/V、尿素下降率(URR)、血钙、血磷、血钾、总CO2、血β2微球蛋白等指标的改善程度与AK-200型血透机差异无统计学意义(P>0.05);采用SWS-4000型血透机维持性血透3个月时,患者的血红蛋白、清蛋白、甲状旁腺激素(PTH)、铁蛋白、转铁蛋白饱和度等指标,与AK-200型血透机差异无统计学意义(P>0.05)。结论SWS-4000型透析机能满足日常血液透析工作需要,能安全有效地治疗尿毒症患者。更多还原

【Abstract】 Objective To evaluate the treatment effect,security and stability of SWS-4000 dialysis machine made in China.Methods Prospective,open and randomized controlled method was used,the study was controlled for imported AK-200 dialysis machine;the object of study were inpatients with chronic kidney failure treated with renal dialysis technology,there were 507cases(8 094 times dialysis)in group of SWS-4000 dialysis machine and 593cases(8 150 times dialysis)in group of AK-200 dialysis machine;the recent and long-term dialysis effect,dialysis complication,dialysate made by machine and so on were observed.ResultsOccurrence rate of hypotension,hypertension,choking sensation in chest,palpitation,nausea,spasticity and so on was not significant difference between both two groups(P>0.05).The error dispersion of SWS-4000 dialysis machine was larger than that of AK-200 dialysis machine,waterway alarm times of SWS-4000 dialysis machine was more than that of AK-200 dialysis machine,sodium concentration of dialysate made by SWS-4000 dialysis machine was higher than that by AK-200 dialysis machine(P<0.05),but it could be corrected by down-regulate the electric conductance of the machine.after one time treatment by SWS-4000 dialysis machine,the KT/V,urea descend rate(URR),blood calcium,phosphorus,kalium,total CO2,β2microglobulin of SWS-4000 group were similar to the AK-200group(P>0.05).After 3months dialysis by SWS-4000 dialysis machine,there were no significant difference of hemoglobin,albumin,parathormone(PTH),ferritin,transferin saturation between two groups(P>0.05).Conclusion The SWS-4000 dialysis machine can effectively and safely treat renal failure patients.更多还原