【摘要】 目的以某院分离所得226株鲍曼不动杆菌为对象,对其感染特点及耐药性进行分析。方法通过MiCroscan Walkaway-40型全自动细菌鉴定系统进行菌种鉴定,采用K-B纸片扩散法进行药敏试验。结果该菌来源以痰液标本为主(占74.8%),科室分布主要在呼吸内科(占38.6%);在16种常用抗生素中,该菌对多黏菌素E、头孢哌酮/舒巴坦和米诺环素的耐药率较低,依次为6.8、17.3和21.2%;但对以往较敏感的碳青霉烯类药物出现了耐药,除了阿米卡星耐药率为67.9%以外,该菌对氨基糖苷类和氟喹诺酮类抗生素耐药率均在80%以上。结论鲍曼不动杆菌耐药严重,且耐药谱存在地区、医院之间差异,应当加强药敏检测,才能有效预防和控制感染。更多还原

【Abstract】 Objective To analyze the infection characteristics and drug resistance of 226 strains of Acinetobacter baumannii from a hospital.Methods The strains identification was implemented through automatic bacteria identification system of MiCroscan type Walkaway-40,the drug sensitivity test was carried out by using K-B disk diffusion method.Results The sources of the bacteria was from sputum specimens(74.8%),distributing mainly in the department of internal medicine(38.6%);Lower rates of bacteria resistant to polymyxin E,cefoperazone/sulbactam and minocycline followed by 6.8%,17.3% and 21.2% in the 16 kinds of antibiotics;But for the past more sensitive to carbapenems appeared resistant,except amikacin was 67.9%,the strain of aminoglycosides and fluoroquinolones antibiotic resistance rates above 80%.Conclusion Acinetobacter baumannii resistant was severe,there was difference between hospitals and regions about resistance spectrum.Therefore,susceptibility testing should be strengthened in order to effectively prevent and control infection.更多还原