【摘要】 目的分析不规则抗体阳性结果,区分非特异性的自身抗体和有意义的同种抗体,指导临床用血。方法使用微柱凝胶卡进行不规则抗体实验,对阳性标本进行自身对照及抗体特异性检测,对自身对照阳性标本进行自身吸收放散处理后检测。结果不规则抗体阳性率0.36%,Rh血型系统抗体占65.71%,13例自身对照阳性经自身吸收放散后证实2例自身抗体、同种抗体同时存在,3例只存在同种抗体,8例非特异性抗体。结论不规则抗体阳性结果原因复杂,与患者疾病、输血史都有很大关系,自身对照阳性并非完全是非特异性抗体,需要进一步实验,保证输血安全。更多还原

【Abstract】 Objective To guide the clinical use of blood by analysing the positive results in irregular antibody detection and distinguishing the non-specific autoantibodies from significant alloantibodies. Methods The irregular antibody detection is performed by microcolumn gel card test. The positive samples are identified the specificity of antibodies based on the selfcontrol test,and after that the absorption and elution test is carried out when the result of self-control is positive. Results The positive rate of irregular antibodies is 0. 36% in which RH groups antibodies account for 65. 71%. 13 cases are positive in the self-control test. In the absorption and elution test,2 cases are confirmed the autoantibodies and alloantibodies existed at the same time,3 cases only contain isoantibody,and 8 cases contain non-specific antibodies. Conclusion The reasons for the production of the irregular antibodies are very complex,There is a great relationship between the disease and the history of blood transfusion. The positive results of the self-control test is not entirely caused by the nonspecific antibodies. So we must ensure the safety of blood transfusion by further experiments.更多还原