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D-二聚体与Lp(a)联合检测在糖尿病合并冠心病中的应用价值
The Clinical Value of Combined Detection of D-dimer and Lp( a) in Diabetic Patients with Coronary Heart Disease
【摘要】 目的探讨D-二聚体(D-dimer)与血清脂蛋白a[Lp(a)]联合检测在糖尿病合并冠心病中的预测价值。方法选择67例糖尿病合并冠心病患者、57例单纯糖尿病患者与76例健康对照者,分别检测D-二聚体与Lp(a)水平。结果糖尿病合并冠心病组D-二聚体与Lp(a)水平明显高于单纯糖尿病组和健康对照组,单纯糖尿病组高于健康对照组,差异均有统计学意义(P<0.05)。结论联合检测D-二聚体与Lp(a))有利于早期检测出糖尿病引起的冠心病,延缓冠心病的进展。
【Abstract】 Objective To explore the predictive value of combined detection of fibrinogen( D-dimer) and serum lipoprotein a [Lp( a) ]in diabetes patients with coronary artery disease. Methods The D-dimer and Lp( a)levels in 67 cases of diabetic patients with coronary heart disease,57 cases of patients with diabetes alone and76 cases of healthy controls were detected. Results The D-dimer and Lp( a) levels in diabetic patients with coronary heart disease group were significantly higher than those in the diabetic group and the healthy controls( P <0.05),and the D-dimer and Lp( a) levels in diabetic group were also significantly higher than that of in healthy controls( P < 0. 05). Conclusion The combined detection of D-dimer and Lp( a)) is conducive to early diagnosis of coronary heart disease caused by diabetes,and delaying the progress of coronary heart disease.
【Key words】 D-dimer; Lipoprotein(a); Diabetic patients with coronary heart disease;
- 【文献出处】 标记免疫分析与临床 ,Labeled Immunoassays and Clinical Medicine , 编辑部邮箱 ,2014年04期
- 【分类号】R587.1;R541.4
- 【被引频次】13
- 【下载频次】55