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抗精神病药物致Q-T间期延长时电解质变化分析

Analysis of electrolyte changes caused by prolonged Q-T interval of antipsychotic drugs

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【作者】 余利英

【Author】 Yu Liying;Department of function,Third People’s Hospital of Meizhou City;

【机构】 广东省梅州市第三人民医院功能科

【摘要】 目的:了解抗精神病药物致Q-T间期延长时电解质的变化。方法:收集自2012年1月~2013年12月在本院住院病人150例,服用各种抗精神病药物后一个月查心电图、血生化。结果:150例患者一个月后心电图正常者89例,Q-T间期延长者27例,其他异常者34例。27例Q-T间期延长中低钾12例,低钙4例,低钾、低钙6例,低钾、低钠1例,低氯1例,正常3例。结论:在临床中应尽量选用对Q-T间期影响较少的抗精神病药物,常规复查心电图、血生化,有Q-T间期延长者可以补充电解质来纠正。

【Abstract】 Objective:Understanding of antipsychotic induced changes of Q-T interval prolongation when electrolyte.Methods from 2012January ~2013 year in December in our hospital 150 patients taking antipsychotic drugs,one month after the check electrocardiogram,blood biochemistry.Methods:Collected from 2012 January ~2013 December in our hospital 150 cases of patients,taking various antipsychotic drugs after a month check electrocardiogram,blood biochemistry.Results:89 cases of 150 patients a month after normal ECG,Q-T interval prolongation in 27 cases,34 cases with other abnormalities.27 cases of Q-T interval prolongation of low potassium in12 cases,4 cases of lowcalcium,low potassium,low calcium in 6 cases,1 cases of low potassium,low sodium,low chlorine in 1 cases,3cases were normal.Conclusion:In clinical practice should be chosen on the Q-T interval effect of antipsychotic drugs less conventional,electrocardiogram,blood biochemistry,a prolonged Q-T interval can be replenished with electrolytes to correct.

  • 【文献出处】 北方药学 ,Journal of North Pharmacy , 编辑部邮箱 ,2014年07期
  • 【分类号】R971.4
  • 【下载频次】49
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