【摘要】 目的了解合肥市耐多药肺结核可疑者筛查情况,探讨可疑者中耐多药/广泛耐药的相关因素。方法收集2012~2013年所有耐多药肺结核可疑者筛查数据,使用SPSS软件进行统计分析。结果全市共筛查耐多药肺结核可疑者344例,其中痰培养阳性114例(33.1%),登记为复治失败、其他、初治3月末涂阳的可疑者痰培养阳性率分别为66.7%、83.3%、16.7%。药敏试验结果为耐多药/广泛耐药病人46例(13.4%),多因素Logistic回归分析显示,60岁及以下、登记为复治失败或其他的可疑者耐多药/广泛耐药的检出率较高。结论合肥市耐多药结核病防治工作要加强重点人群的耐药检测,提高实验室痰培养阳性率。更多还原

【Abstract】 Objective To realize screening situation of suspicious multi- drug resistant tuberculosis( MDR- TB) cases in Hefei,and explore related factors of MDR or extensively drug resistant tuberculosis( XDR- TB) in suspicious patients.Methods We collected data of 344 suspicious MDR- TB in 2012- 2013,and analyzed demographic characteristics,results of sputum culture and drug susceptibility test( DST). Results A total of 344 cases were screened,with 33. 1% sputum culture- positive. The rate of registration for retreatment failed,the other,and sputum culture- positive in the end of third month were 66. 7%,83. 3% and 16. 7% respectively. 46 cases( 13. 4%) were MDR- TB / XDR- TB by DST. Multiple logistic regression analysis showed that suspicious patients who were 60 years old or less than 60 years old,registered for the retreatment failed had a higher detection rate. Conclusion High risk groups screening should be strengthened for Hefei MDR- TB prevention and control work,so as to improve sputum culture- positive rate.更多还原