【摘要】 采用动态法测定了常压下R-α-苯乙胺-D-酒石酸和S-α-苯乙胺-D-酒石酸非对映体盐在甲醇、乙醇、DMF和丙酮与水体积比为5∶2的溶液中的溶解度.在这几种溶剂中,两种非对映体盐的溶解度随温度的升高而增大.用简化方程、Apelblat方程和四参数多项式对溶解度数据进行了关联,其平均绝对相对偏差的范围分别为0.66<AARD<2.67,0.72<AARD<7.69,1.09<AARD<13.64.更多还原

【Abstract】 The solubility of R-α-phenylethylamine-D-tartrate and S-α-phenylethylamine-D-tartrate in methanol,ethanol,DMF and a solvent mixture of acetone and water with the volume ratio of 5∶ 2 were measured by dynamic method under atmospheric pressure.The solubility of the two salts in the above mentioned solvent systems increase with increasing temperature.The experimental data were correlated with simplified equation,Apelblat equation and the polynomial equation,the ranges of average absolute relative derivation(AARD) were 0.66 < AARD < 2.67,0.72 < AARD < 7.69,1.09 < AARD < 13.64,respectively.更多还原