【摘要】 目的观察急性脑梗死患者谵妄状态持续存在的危险因素及其预后。方法记录127例出现谵妄状态的急性脑梗死患者的年龄、性别、基础疾病、既往认知功能状态、谵妄状态的类型、NIHSS评分、MMSE评分和GCS评分等。记录患者的住院时间、改良Barthel指数评分及死亡等情况。采用SPSS17.0统计软件分析患者出现持续性谵妄状态的危险因素及预后。结果①127例出现谵妄状态的脑梗死患者中,持续性谵妄状态患者46例,占36.2%;非持续性谵妄状态患者81例,占63.8%。持续性谵妄状态组和非持续性谵妄状态组患者在年龄、性别、既往认知功能状态、NIHSS评分和GCS评分方面差异无统计学意义。②急性脑梗死患者出现持续性谵妄状态的危险因素有基础疾病≥3个、肺部感染、抑制型谵妄状态及MMSE评分低。③持续性谵妄状态患者的平均住院时间大于非持续性谵妄状态患者;而3月后的改良Barthel指数评分明显低于非持续性谵妄状态患者;死亡患者的比例高于非持续性谵妄状态患者。结论急性脑梗死患者谵妄状态持续性的危险因素有基础疾病≥3个、肺部感染、抑制型谵妄状态及MMSE评分低。出现持续性谵妄状态的急性脑梗死患者的住院时间延长,日常生活能力降低,死亡率升高。更多还原

【Abstract】 ObjectiveTo investigate the risk factors and prognosis of acute cerebral ischemia patients suffered from persistent delirium.MethodsA total of 127 patients suffered from acute cerebral ischemia with delirium were included. To make note each patient’s age, gender, comorbid diseases, previous cognitive function, the type of delirium, scores of NIHSS, MMSE and GCS, length of stay in hospital, scores of modified Barthel index and death, etc. Then analyzed the risk factors and prognosis of the patients with persistent delirium by SPSS17.0.Results1. There were 46 patients suffered from persistent delirium who account for 36.2 percent of 127 acute cerebral ischemic patients with delirium. 81 patients suffered from non-persistent delirium who account for 63.8 percent. There were no statistical difference in age, gender, previous cognitive function, and scores of NIHSS and GCS between persistent delirium patients and non-persistent delirium patients. 2. The risk factors of acute cerebral ischemic patients who developed persistent delirium are more than three comorbid diseases, pulmonary infection, hypoactive delirium and low MMSE score. 3. The acute cerebral ischemic patients who developed persistent delirium stayed in hospital longer than non-persistent patients. The scores of modified Barthel index of persistent delirium patients were lower than that of non-persistent patients in three months. The death rates of persistent delirium patients were higher than that of non-persistent patients.ConclusionThe risk factors of acute cerebral ischemic patients who developed persistent delirium are more than three comorbid diseases, pulmonary infection, hypoactive delirium and low MMSE score. The acute cerebral ischemic patients who developed persistent delirium will stay longer in hospital. Their daily living capability will decrease and their death rates will increase.更多还原