【摘要】 目的:探讨康艾注射液对恶性肿瘤化疗患者的减毒增效作用及肾脏保护作用。方法:采用随机、对照及单盲研究的设计方案,分别为化疗联合中药康艾注射液治疗组和单纯化疗对照治疗组。共入选患者32例,其中男性19例,女性13例。两组患者性别、年龄、病程等方面差异无统计学显著性意义。通过检测患者肾功能、尿微量蛋白水平及患者中医症候评价积分等多种临床相关因素进行分析。结果:康艾注射液治疗组患者的整体状况及肾脏功能等均优于对照组。结论:康艾注射液可以减轻恶性肿瘤化疗导致的肾脏损害程度、特别是尿微量蛋白如尿α1微球蛋白(α1-MG),尿β2微球蛋白(β2-MG)和尿视黄醇结合蛋白(RBP)的动态指标可以发现明显的改善,提高患者的生活质量。更多还原

【Abstract】 Objective:To discuss the protecting renal function by Kangai injection in cancer patients undergoing chemotherapy.Method:The randomized,controlled and single-blind study was used.The kidney function and urine trace protein levels were detected and traditional Chinese medicine(TCM) symptoms were evaluated,and other related symptoms were analyzed.Result:The general situation and renal function in treatment groupwas better than the control group.Conclusion:Kangai injection can reduce kidney damage and improve survival situation.更多还原