【摘要】 目的:考察消郁安神胶囊中挥发油β-环糊精包合物的热稳定性。方法:采用GC-MS测定挥发油β-环糊精包合物于不同温度下百秋李醇含量。色谱条件为HP-5毛细管色谱柱(0.25 mm×30 m,0.25μm),Sim模式选择离子模式,检测器电压1.5 kV。结果:挥发油包合物于40,60,80℃加热4 h,百秋李醇含量未发生明显变化。结论:消郁安神胶囊中挥发油β-环糊精包合物热稳定性良好,可用于指导该制剂成型工艺设计。更多还原

【Abstract】 Objective: To observe thermal stability of β-cyclodextrin inclusion complex of volatile oil from Xiaoyu Anshen capsules.Method: The content of patchouli alcohol at different temperatures from β-cyclodextrin inclusion complex of volatile oil was determined by GC-MS.Chromatographic conditions were as follows: HP-5 capillary column(0.25 mm × 30 m,0.25 μm),took selective ion mode(SIM),voltage of detector set at 1.5 kV.Result: The content of patchouli alcohol was no significant change after inclusion complex of volatile oil heating 4 h at different temperatures(40,60,80 ℃).Conclusion: Thermal stability of β-cyclodextrin inclusion complex of volatile oil from Xiaoyu Anshen capsules was good,it could guide molding process of this preparation.更多还原