【摘要】 目的:探讨胆总管结石合并2型糖尿病患者行腹腔镜胆总管切开取石术(LCBDE)的可行性、安全性及有效性。方法:回顾性分析2009年12月—2012年12月采用LCBDE治疗的58例合并2型糖尿病(糖尿病组)及同期58例无糖尿病(非糖尿病组)胆总管结石患者的临床资料,比较两组术前、术中及术后的情况。结果:两组患者手术时间、术中出血量、开始进食时间、术后住院时间及中转开腹方面,差异均无统计学意义(t/χ2=3.921,6.940,1.332,1.270,0.342,均P>0.05)。两组术后电解质紊乱、胆管炎、胆瘘、切口感染、肺部感染发生率比较,差异亦均无统计学意义(χ2=0.438,0.537,0.342,1.036,0.342,均P>0.05)。两组均无术后结石残余、胆管狭窄及死亡病例。结论:合并2型糖尿病的胆总管结石患者在围手术期严格控制血糖,术中仔细操作的前提下,行LCBDE是可行的、安全的、有效的。更多还原

【Abstract】 Objective:To study the feasibility,safety and efficacy of laparoscopic common bile duct exploration(LCBDE) for removal of common bile duct(CBD) stones in patients with concomitant type 2 diabetes.Methods:The clinical data of 58 CBD patients with type 2 diabetes(diabetic group),and another 58 non-diabetic CBD patients(non-diabetic group) undergoing LCBDE procedures from December 2009 to December 2012 were retrospectively analyzed.The pre-,intra- and postoperative conditions between the two groups were compared.Results:Results of the comparisons showed no significant differences between the two groups in the operative time,intraoperative blood loss,time to liquid intake and length of postoperative stay(t/χ2=3.921,6.940,1.332,1.270 and 0.342.all P>0.05),and also no significant differences between the two groups in the incidences of postoperative electrolyte imbalance,cholangitis,bile leakage,wound infection and pulmonary infection(χ2=0.438,0.537,0.342,1.036 and 0.342.all P>0.05).No residual stones,bile duct stricture or death were noted in either group after operation.Conclusion:LCBDE for CBD stone removal in patients with type 2 diabetes,based on the premise of preoperative glycemic control and meticulous surgical technique,is feasible,safe and effective.更多还原