【摘要】 目的探讨累计妊娠率的相关因素。方法选取本生殖中心2010年11月至2013年6月完成一次取卵周期的患者为研究对象,比较年龄、获MⅡ卵比率、受精率、正常受精率、囊胚形成率和可移植胚胎率与累计临床妊娠率的相关性,并对相关因素进行深入探讨。结果年龄、囊胚生成率和可移植胚胎率与累计临床妊娠率相关。其中,30岁以下组累计妊娠率明显高于30岁以上组(卡方检验P<0.05)。有囊胚生成组累计妊娠率显著高于无囊胚生成组(卡方检验P<0.05)。可移植胚胎率(ETR)>75%组累计妊娠率高于50%<ETR≤75%组,更高于ETR≤50%组,各组间妊娠结局均有差异(卡方检验P<0.05)。结论年龄、囊胚生成率和可移植胚胎率与累计妊娠率相关。30岁以下具有较高的临床妊娠率;非优质胚胎囊胚培养在预测累计妊娠率上有一定价值;可移植胚胎率在一次取卵周期累计妊娠率中有强提示作用。更多还原

【Abstract】 Objective To explore IVF productivity rate(or cumulative pregnancy rate per collection cycle) correlated factors. Methods Patients completed an oocyte retrieval cycle in our reproductive medicine center from November, 2010 to June, 2013 were chose as the study objects. The correlation between age, MII oocyte ratio, fertilization rate, normal fertilization rate, blastocyst formation rate(BFR), embryo transfer rate(ETR) and productivity rate were analyzed. And the relevant factors were explored further. Results Age, BFR and ETR were related with productivity rate. Productivity rate of less than 30 years old group was higher than more than 30 years old group(chi-square test, P<0.05). Productivity rate of blastocyst formed group was higher than no blastocyst formed group(chi-square test, P<0.05). The pregnancy outcome among ETR>75% group, 50%<ETR ≤75% group and ETR≤50% group were different(chi-square test, P<0.05). Conclusions Age, blastocyst formation rate and embryo transfer rate were correlated with productivity rate. Less than 30 years had higher clinical pregnancy rate. Blastocyst culture of poor quality embryo has certain value in the prediction of productivity rate. Embryos transfer rate has strong implications in prediction of productivity rate.更多还原