【摘要】 目的分析住院老年阿尔茨海默病患者医院感染的危险因素。方法回顾调查368例老年阿尔茨海默病住院患者资料和护士交班记录。使用SPSS 15.0统计软件进行条件Logistic回归分析。结果共发生医院感染95例(25.81%),116例次。日常生活能力差(OR=8.398,95%CI:5.343~12.098)、侵入性操作(OR=2.842,95%CI:1.445~3.365)、自知力差(OR=4.457,95%CI:2.789~8.853)、长期服用抗菌药(OR=3.348,95%CI:1.693~6.336)、长期卧床(OR=3.258,95%CI:1.583~6.154)、服用抗精神病药物(OR=2.243,95%CI:1.427~5.583)为医院感染的独立危险因素,定时开窗通风是独立保护因素(OR=0.546,95%CI:0.334~0.867)。结论做好基础及生活护理,减少侵入性操作,合理规范抗生素的使用,密切观察抗精神病药物的副作用,加强消毒隔离措施,可减少老年阿尔茨海默病患者医院感染的发生。更多还原

【Abstract】 Objective To investigate the factors associated with hospital infection in old inpatients with Alzheimer’s disease.Methods 368 old inpatients with Alzheimer’s disease were reviewed and analyzed with Logistic regression.Results There were 95 cases(25.81%) suffered in hospital infection to 116 case-times.As multivariate regression analysis,activities of daily living(OR=8.398,95% CI: 5.343~ 12.098),invasive intervention(OR=2.842,95%CI: 1.445~3.365),no insight(OR=4.457,95%CI: 2.789~8.853),long-term use of antibiotics(OR=3.348,95%CI: 1.693~6.336),chronic in bed(OR=3.258,95%CI: 1.583~6.154),and antipsychotic drug(OR=2.243,95%CI: 1.427~ 5.583) increased the risk of hospital infection independently,and ventilated timely(OR=0.546,95%CI: 0.334~0.867) reduced the risk.Conclusion Good performance of basic and living nursing,less invasive intervention,reasonable use of antibiotics,antipsychotic monitoring,and intensive sterilization may reduce the incidence of hospital infection in inpatients with Alzheimer’s disease.更多还原