【摘要】 硫化氢（H₂S）是继一氧化氮（NO）和一氧化碳（CO）后新发现的第三种内源性气体信号分子,在机体内发挥广泛的生物学效应。已有实验证实,H₂S参与多个器官缺血-再灌注损伤的病理生理过程,H₂S在心肌缺血-再灌注损伤中的作用已有深入研究,但在脑缺血-再灌注损伤中的作用尚未明确阐述。本文主要基于现有的相关文献,旨在阐明H₂S与脑缺血-再灌注损伤的关系,并论述其可能的细胞和分子学机制。更多还原

【Abstract】 Hydrogen sulfide（H₂S） is the third kind of endogenous gaseous signal molecules newly discovered after nitric oxide and carbon monoxide,and plays a wide range of biological roles in the body.It has been proved that H₂S participates in the pathophysiological process of multiple organ ischemia- reperfusion injury.However,the effects of H₂S on cerebral ischemia- reperfusion injury have not been clearly clarified.This paper intends to illustrate the relationship between H₂S and cerebral ischemia- reperfusion injury based on the current literatures,and discuss the possible cellular and molecular mechanisms.更多还原