【摘要】 目的:评价新型除草剂氯胺嘧草醚的急性毒性,为制定生产和应用过程中的防护措施提供依据。方法:按GB15670-1995《农药登记毒理学试验方法》进行。结果:氯胺嘧草醚对雌雄大鼠的急性经口LD50均大于5000 mg/kg;急性吸入LC50>2000 mg/kg;对新西兰种兔的急性眼刺激积分指数(I.A.O.I.)最高值为4;眼刺激平均指数(M.I.O.I.)48 h后为0;皮肤刺激强度平均分值为0。结论:氯胺嘧草醚经口和经皮毒性属于低毒,吸入毒性属于低毒,对眼睛和皮肤均无刺激性。更多还原

【Abstract】 Objective To assure whether this new herbicide is acute toxic or not,and also provide the basis for the development of protective measures in the production and application process.Methods The experiment was done according to GB15670-1995.Results The acute oral toxicity(LD50) of chloramine pyriminobac-methyl to paroecious rats was more than 5000 mg/kg,The acute dermal toxicity(LD50) was more than 2000 mg/kg.The acute inhalation toxicity(LC50) exceeded 2000 mg/kg.The highest index of eye irritation on rabbits was 4,and the mean index of eye irritation was 0.The mean index of skin irritation on rabbits was 0.Conclusion The oral and dermal toxicity of chloramine pyriminobac-methy were graded as low.The acute inhalation toxicity was low,and non-irritation to eyes and skin.更多还原