Objective To explore the effects of infections with hepatitis B virus(HBV)and with Schistosome japonicum on human hepatic fibrosis. Methods Hepatic fibrosis in 59 patients with splenomegaly and hypersplenism was staged by liver histology on wedge liver biopsies.S.japonicumeggs from liver tissue were examined by microscope.Serology of HBV including HBsAg,HBsAb,HBeAg,HBeAb,and HBcAb was assessed by ELISA.Clinical symptoms and laboratory(lab)parameters including routine blood test,liver function tests,and seru...