【摘要】 目的了解Ⅰ类切口手术抗菌药物的使用及存在问题,提高预防使用抗菌药物的规范化水平。方法采用回顾性调查方法,对218例Ⅰ类切口手术患者预防使用抗菌药物的合理性进行分析评价。结果 218例手术病例中预防性使用抗菌药物140例,使用率为64.2%;主要集中在选用第一、二代头孢菌素和氨曲南;术前2h抗菌药物使用率占38.6%,术后达61.4%;用药持续时间<24h的仅为15.7%;抗菌药物选用、用药时机、用药持续时间等仍存在不合理现象。结论Ⅰ类切口手术不规范预防使用抗菌药物较普遍,应采取相关措施促进临床合理使用抗菌药物。更多还原

【Abstract】 OBJECTIVE To investigate and analyze the prophylactic use of antibiotics for type Ⅰ incision surgery and improve the standard prophylactic use of antibiotics.METHODS The prophylactic use of antibiotics for 218 patients undergoing type Ⅰ surgery were retrospectively investigated and analyzed.RESULTS Of 218 patients investigated,there were 140 cases of patients who used antibiotics with the utilization rate of 64.2 %.The first-generation cephalosporins,the second-generation cephalosporins and aztreonam were the most frequently used antibiotics.Only 38.6% of the patients received antibiotics 2 hours before the surgery,and 61.4% of the patients did not received antibiotics until the surgery was completed.Only 5.7% of the patients were with the medication duration less than 24 hours.The use of antibiotics,medication timing,and medication duration remained unreasonable.CONCLUSION The inappropriate use of prophylactic antibiotics is so common in the typeⅠincision surgery that it is necessary to take the corresponding measures to promote the reasonable use of antibiotics.更多还原