【摘要】 目的探讨经皮肝穿刺胆道引流(PTCD)及胆道支架治疗恶性梗阻性黄疸的安全性及短期疗效。方法回顾性分析PTCD及胆道支架治疗恶性梗阻性黄疸患者112例,选择其中具有完整资料的78例作为研究对象,其中PTCD19例,胆道引流及胆道支架植入治疗59例。评价其手术成功率、临床疗效及并发症发生率。结果 78例经皮肝穿刺技术成功率100%,术后1周总胆红素平均水平从术前的(373.2±150.7)μmol/L降至(135.6±60.7)μmol/L(P<0.001),肝功能改善明显。总体有效率为88.46%(69/78),平均生存时间为10.7个月。结论 PTCD联合胆道支架是一种安全、有效的治疗恶性梗阻性黄疸的治疗手段,可有效改善肝功能,为进一步治疗肿瘤创造条件。更多还原

【Abstract】 To assess the security and short-term curative effect of percutaneous transhepatic cholangial drainage(PTCD) combined with stenting therapy for malignant obstruction jaundice. Methods 112 cases with malignant ob- struction jaundice accepted PTCD and stenting, chose 78 cases with complete clinical data as the research object. 19 cases ac- cepted PTCD, 59 cases accepted PTCD and biliary stent implantation. Evaluated the procedure success rates, clinical curative effect and the incidence of complications. Results 78 cases were treated technological successful(100%). The total bilirubin of average decreased from(373.2±150.7)μmol/L to(135.6±60.7)μmol/L 1 week after the procedure(P<0.001). Liver function improved significantly. The lately clinical effective rate was 88.46%(69/78). The average survival time was 10.7 months. Con- clusion PTCD combined with stenting is a safe and effective palliative method for malignant obstruction jaundice. It can im- prove effectively live function and create the conditions for the further treatment.更多还原