【摘要】 目的比较新型带负电荷硫酸钙/β-磷酸三钙复合骨水泥(BCC骨水泥)与甲基丙烯酸甲酯骨水泥(PMMA骨水泥)用于椎体成形术的生物力学性能,探讨BCC骨水泥用于椎体成形术的可能性。方法采用4具老年男性骨质疏松性尸体胸腰段脊柱标本,建立椎体压缩性骨折的模型,随机分为2组,每组8例,分别以2 ml/min注入BCC组和PMMA组的骨水泥,测试术前、术后椎体的强度和刚度的变化。结果 BCC组和PMMA组骨折前与骨折治疗后最大载荷间的差异具有统计学意(P<0.05),且两组治疗后的最大载荷均高于骨折前;而BCC组和PMMA组骨折前与骨折治疗后刚度间的差异均无统计学意义(P>0.05)。结论 BCC骨水泥椎体成形术能强化骨质疏松性椎体压缩性骨折,达到生物力学要求。更多还原

【Abstract】 Objective To compare the biomechanics of the novel bone cement,negative charge-containing calcium sulfate/β-phosphate tri-calcium composite(BCC) bone cement,and methyl methacrylate(PMMA) bone cement in vertebroplasty,and to explore the possibility of application of BCC bone cement in vertebroplasty.Methods The model of vertebral compression fractures was established using thoracolumbar spine specimens from 4 elderly male cadavers.Then they were randomly divided into 2 groups,and each group had 8 vertebrae.BCC bone cement and PMMA bone cement was injected at the speed of 2 ml/min.The changes of the strength and stiffness of the vertebral body were detected before and after the operation.Results The difference of the maximum load before and after fracture between BCC group and PMMA group was statistically significant(P<0.05),and the maximum load was higher after fracture than that before fracture in the both groups.No significant difference of stiffness in both BCC group and PMMA group was observed(P>0.05).Conclusion Vertebroplasty using BCC bone cement can strengthen osteoporotic vertebral compression fractures and meet the requirements of biomechanics.更多还原