【摘要】 目的 探讨血浆置换治疗急性乙烯利中毒的临床效果。方法 对山东省滨州医学院附属医院急诊科2010年1月至2012年12月急性乙烯利中毒患者的临床资料进行回顾性分析。将急性乙烯利中毒患者分为2组,2011年9月至2012年12月收治的患者38例为观察组,2010年1月至2011年8月收治的患者35例为对照组。对照组给予洗胃、导泻、灌肠等常规综合治疗,观察组在对照组治疗的基础上,加用血浆置换治疗。观察治疗过程中患者昏迷例数,记录昏迷时间、住院时间及患者存活时间,统计患者死亡情况并加以比较。结果 观察组平均住院时间、昏迷发生率、昏迷时间及病死率明显少于对照组[分别为(6.4±1.6)d比(12.1±2.2)d,15.8%(6./38)比51.4%(18/35),(9.4±2.1)h比(21.3±3.8)h,5.3%(2/38)比25.7%(9/35)],平均存活时间明显长于对照组[(9.7±2.8)d比(3.6±1.2)d],差异均有统计学意义(均P<0.05)。结论 血浆置换治疗急性乙烯利中毒可提高疗效。更多还原

【Abstract】 Objective To investigate the clinical curative effect of the plasma exchange in the treatment of acute ethylene poisoning.Methods From January 2010 to December 2012,the clinical data of acute ethylene poisoning patients in department of emergency was retrospectively analyzed.The acute ethylene poisoning patients were divided into two groups:the observation group(treated with plasma exchange,38 cases) and the control group(routine therapy,35 cases).The patients in control group were treated with routine therapy,while the patients in observation group underwent plasma exchange and the routine therapy.The incidence rate of coma,the coma time,hospitalization time,survival time and the mortality were observed and compared in two groups.Results The average hospitalization time,the incidence of coma,coma time and the mortality in observation group were lower than those in control group[(6.4 ± 1.6)d vs(12.1 ±2.2)d,15.8%(6/38) vs 51.4%(18/35),(9.4±2.1)hvs(21.3±3.8)h,5.3%(2/38) vs 25.7%(9/35)];the mean graft survival time was longer than that in control group[(9.7±2.8) dvs(3.6±1.2)d],and there were significant differences(all P < 0.05).Conclusion Plasmapheresis can significantly increase the effect on acute toxic of ethephon.更多还原