【摘要】 目的:了解抗菌药物专项整治活动后某院住院患者抗菌药物的应用情况,为进一步干预抗菌药物不合理使用提供参考。方法:采用回顾性统计方法,对该院2011年7-12月、2012年1-6月、2012年7-12月住院患者抗菌药物应用指标、各级抗菌药物使用情况、DDDs排序列前10位的抗菌药物使用情况进行统计、分析。结果:住院患者多数抗菌药物应用指标不断改善,3个时期住院患者抗菌药物使用率分别为95.05%、85.81%和67.91%,抗菌药物使用强度分别为60.93、47.93和41.22 DDDs/100人/天,Ⅰ类切口手术患者预防用抗菌药物比例分别为99.33%、76.98%和19.91%。3个时期抗菌药物使用均以非限制使用级抗菌药物为主,DDDs分别为12 514.95(89.19%)、8 095.26(77.57%)和6 797.17(72.47%);限制使用级抗菌药物的使用呈上升趋势,DDDs分别为1 479.39(10.54%)、2 251.35(21.57%)和2 514.57(26.81%);特殊使用级抗菌药物少有使用,DDDs分别为37.00(0.26%)、90.00(0.86%)和68.00(0.72%)。结论:专项整治活动的开展提高了该院住院患者抗菌药物合理使用水平,但仍需加强对Ⅰ类切口手术抗菌药物预防使用时机不当、使用疗程过长的干预,并控制限制使用级抗菌药物的使用。更多还原

【Abstract】 OBJECTIVE:To investigate the use of antibacterial drugs in the inpatients of a hospital after special rectification so as to provide reference for the intervention of irrational use of antibacterial drugs.METHODS:By retrospective survey analysis,the utilization indicators of antibacterial drugs in the inpatients,use of different levels of antibacterial drugs,use of top 10 antibacterial drugs in terms of DDDs were analyzed statistically during Jul.-Dec.in 2011,Jan.-Jun.in 2012 and Jul.-Dec.in 2012.RESULTS:Most utilization indicators of antibacterial drugs were improved after special rectification.The utilization ratios of antibacterial drugs for inpatients in the three periods were 95.05%,85.81% and 67.91%,respectively.The antibacterial use densities were 60.93,47.93,and 41.22 DDDs/100 persons/day,respectively.The proportions of prophylactic application of antibacterial drugs in type Ⅰ incision surgery were 99.33%,76.98%,and 19.91%,respectively.Unrestricted-use antibacterial drugs took up predominate place in the list of DDDs,which were 12 514.95(89.19%),8 095.26(77.57%),and 6 797.17(72.47%)in the three periods.The use of restricted-use antibacterial drugs increased in DDDs,which were 1 479.39(10.54%),2 251.35(21.57%)and 2 514.57(26.81%),respectively.Antibacterial drugs for special use were used a little in DDDs,which were 37.00(0.26%),90.00(0.86%),and 68.00(0.72%),respectively.CONCLUSIONS:The special rectification promotes rational use of antibacterial drugs in the inpatients of the hospital.However,further management should be taken to interrupt the irrational administration timing of antibacterial drugs,the long course of antibacterial drugs use and excessive use of restricted-use antibacterial drugs.更多还原