【摘要】 目的:调查我院治疗耐甲氧西林金黄色葡萄球菌(MRSA)感染的抗菌药物使用情况,分析导致抗感染失败的原因。方法:收集2011年在我院进行抗MRSA感染治疗的患者资料,在美国感染性疾病学会2011年发布的《耐甲氧西林金黄色葡萄球菌感染的循证治疗指南》以及我国《耐甲氧西林金黄色葡萄球菌感染防治专家共识》的基础上,从患者的基本情况、感染部位、药敏数据与选用的抗感染药物的品种、剂量、疗程等方面对治疗效果进行评价。结果:我院MRSA感染的治疗方案与指南的推荐基本相符,但仍存在选药不当与用药剂量过小的问题。结论:应充分发挥临床药师的作用,为抗MRSA感染提供服务,提高MRSA感染的治愈率。更多还原

【Abstract】 OBJECTIVE:To investigate the use of antibiotics for Methicillin-resistant Staphylococcus aureus(MRSA) infection in our hospital,and to analyze the cause of anti-infection failure.METHODS:The data of patients receiving anti-infection treatment of MRSA were collected from our hospital in 2011.Therapeutic efficacy was evaluated in terms of basic situation of patients,infection site,susceptibility data,varieties,dose and course of anti-infection agents based on IDSA GUIDE in 2011 and the Same Minds of Experts in ChinaRESULTS:The treatment regimen of MRSA in our hospital corresponded with guideline mainly,but there were some problems about drug selection and drug dosage.CONCLUSIONS:Clinical pharmacists must play a role on treatment of MRSA infection to improve cure rate.更多还原