【摘要】 脊椎动物生殖过程涉及到一系列信号通路的调控,Kisspeptin/GPR54系统对GnRH脉冲释放的激活起重要作用,是性发育启动和脊椎动物生殖的调节器。Kisspeptin能通过GPR54受体激活多种信号,以发挥功能。本文首先对参与脊椎动物生殖调控的Kisspeptin/GPR54系统的概念与发现做简要叙述,并进一步就Kisspeptin/GPR54系统如何调控脊椎动物生殖方面做一综述。更多还原

【Abstract】 Vertebrate’s reproduction was regula ted by series of signaling pathways.Kisspeptin/GPR54 system is the regulator of vertebrate’s sexual development beginning and reproduction because Kisspeptin/GPR54 can activate the pulsatile release of GnRH.Kisspeptin with its GPR54 receptor give full play to their functions via activating variety of signals.This review introduce the conception and discovery of Kisspeptin/GPR54 system first then give a further explanation on the important role that Kisspeptin/GPR54 system play in vertebrate ’s reproduction.更多还原