【摘要】 目的探讨延安市某医院2006-2010年皮肤科门诊患者真菌感染的菌群分布、特点及变迁情况,为临床防治真菌感染提供研究依据。方法采用回顾性调查方法,收集5年来该院皮肤科门诊患者的所有真菌检查的病例资料,对标本来源、菌群分布及菌种变迁进行调查和分析。结果 5年中真菌感染阳性率为9.98%~44.05%,男性感染率高于女性,浅部真菌感染率高于深部真菌,差异均有统计学意义(P<0.005);60岁以上患者占38.18%,感染以白假丝酵母菌为主但所占比例5年间下降了16.86%(P<0.05),而其他假丝酵母菌所占比例则呈上升趋势。结论 5年来该院真菌感染菌群分布发生了变迁;真菌感染以老年男性为主,儿童真菌感染亦不容忽视,临床应加强对这些真菌感染的预防和监测,防止真菌感染。更多还原

【Abstract】 Objective To explore the pathogenic fungi distribution,characteristics and diversify information of dermatology outpatients in a hospital of Yan’an from 2006 to 2010,and provide the evidence for the clinical prevention and treatment of fungal infections.Methods All cases of outpatients with fungal infection data in recent S years were retrospectively investigated and analyzed,mainly on the source,distribution and changes of fungal speciments.Results The fungal infection rate had been 9.98%-44.05%in the past five years.The infection rate of men was higher than women,the rate of superficial fungal higher than deep fungus(P < 0.005);The age of patients above 60 yr accounted for 38.18%,Candida albicans remained the main pathologcal fungus,its constituent ratio decreased 16.86%(P <0.005),while other Candidas was on the rise.Conclusion In the past five years,the distribution of fungal infection had changed in the hospital;fungal infections are primarily found in male elder people and children.Prevention and monitoring for clinical fungal infections should be strengthened.更多还原