泮托拉唑和奥美拉唑治疗急性脑血管病并发应激性溃疡出血疗效对比分析

【摘要】 目的:采用随机分类方法,观察两种方法治疗急性脑血管病并发应激性溃疡出血疗效。方法:将84例急性脑血管病患者随机分为两组,泮托拉唑组42例给予泮托拉唑40mg加入生理盐水或5%葡萄糖注射液100ml静滴,维持30～60分钟,1次/日,共10天;奥美拉唑组42例给予奥美拉唑40mg加入0.9%生理盐水或5%葡萄糖注射液100ml静脉点滴,维持30～60分钟,1次/日,共10天。结果:泮托拉唑组总有效率90.3%,奥美拉唑组总有效率66.5%,差异有显著性(P<0.05)。两组不良反应比较,差异没有显著性(P>0.05)。结论:泮托拉唑比奥美拉唑更能有效的治疗急性脑血管病并发应激性溃疡出血,安全可靠。更多还原

【Abstract】 Objective:Use the method of Random assortment and observe curative effect of the two ways in treating cute cerebrovascular disease complicated with stress ulcer.Methods:Put 84 patients randomly divided into two groups.42 cases of Pantoprazole group:add 0.9% of physiological saline or 100ml of 5% glucose injection,infusion solution,into 40mg of Pantoprazole.Last for 30min to 60min,quaque die for 10 days.42 cases of Omeprazole group:add 0.9% of physiological saline or 100ml of 5% glucose injection,infusion solution,into 40mg of Omeprazole.Last for 30min to 60min,quaque die for 10 days.Result:The clinical efficacy rate of Pantoprazole is 90.3%.The clinical efficacy rate of Omeprazole is 66.5%.The difference of the two groups was significant(P<0.05).Comparing the adverse reaction of the two groups,the difference of the two groups wasn’t significant(P>0.05).Conclusion:Pantoprazole is more effective,safe and reliable than Omeprazole in treating acute cerebrovascular disease complicated with stress ulcer bleeding更多还原