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伴有血小板减少的川崎病临床特点总结

Summarization of clinical characteristics of Kawasaki disease combined with thrombocytopenia

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【作者】 李艳春陈显秋张云峰鲁继荣成焕吉李善玉

【Author】 LI Yan-Chun,CHEN Xian-Qiu,ZHANG Yun-Feng et al.Department of Pediatrics,the First Hospital of Jilin University,Changchun 130021,Jilin,China

【机构】 吉林大学第一医院儿科吉林大学第一医院检验科

【摘要】 目的:了解伴有血小板减少的川崎病的特点。方法:回顾性分析近5年诊治的4例伴有血小板减少的川崎病患者的临床资料。结果:患儿发病后5~8天出现血小板下降,且下降的数值不固定,平均血小板数值为47.5×109/L,发病后9~12天血小板恢复正常;发生冠状动脉病变的几率为50%,病情多较重,病变累及多个脏器,误诊率及延误诊治的几率高。结论:伴有血小板减少的川崎病发生多系统并发症的几率高,应给予足够的重视;对于病程早期即出现血小板减少、全身多脏器损伤的病例,要考虑重型川崎病的可能,早期给予静脉点滴丙种球蛋白治疗,以减少并发症的发生。

【Abstract】 Objective:To understand the clinical characteristics of Kawasaki disease combined with thrombocytopenia.Methods:The clinical data of cases with Kawasaki disease combined with thrombocytopenia were analyzed retrospectively.Results:Platelet began to descend after 5-8 days of onset with varying degrees;the average platelet count was 47.5×109/L,then it returned to normal at 9-12 days after onset;the incidence rate of coronary artery lesions was 50%;the conditions of patients were usually severe and several organs were involved;the rate of misdiagnosis and delayed diagnosis were high.Conclusion:The rate of multiple organs injury is high in the cases with Kawasaki disease combined with thrombocytopenia,it is necessary for pediatric doctors to pay much attention to this disease.For those cases who present thrombocytopenia and multiple organs injury,Kawasaki disease should be one of consideration,and gamma globulin should be used to decrease the occurrence of complications.

【关键词】 川崎病血小板减少儿童
【Key words】 Kawasaki diseaseThrombocytopeniaChild
  • 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2013年09期
  • 【分类号】R725.4
  • 【被引频次】4
  • 【下载频次】204
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