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阻塞性睡眠呼吸暂停低通气综合征合并COPD患者肺功能特点分析

The analysis of pulmonary function in OSAHS with COPD patients

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【作者】 丁卫东傅江涛黄庆琳杨晓红

【Author】 DING Weidong FU Jiangtao HUANG Qinglin YANG Xiaohong Department of Otolaryngology Head and Neck surgery of Lishui City in Zhejiang Province,Lishui 323000,China

【机构】 浙江省丽水市人民医院耳鼻咽喉头颈外科

【摘要】 目的研究重叠综合征(OS)与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者在肺功能上的变化差异。方法随机选择56例患者将其分为两组,OS组28例,单纯OSAHS组28例,比较两组患者多导睡眠图、静态肺功能检查及血气分析的差异。结果 1)OS组的最低SaO2%低于单纯OSAHS组(P<0.05),Lat、AHI高于单纯OSAHS组(P<0.05)。2)OS组PaCO2高于单纯OASHS组(P<0.05),而PaO2及SO2低于单纯OSAHS组(P<0.05)。3)两组患者FVC%、FEV1%、FEV1/FVC%均低于单纯OSAHS组(P<0.05)。结论 OS患者较单纯OSAHS患者夜间缺氧更明显,日间肺功能损害更严重。

【Abstract】 Objective To explore the difference in pulmonary function between overlap syndrome(OS) and obstructive sleep apnea hypopnea syndrome(OSAHS)patients.Methods 56 patients who were randomly recruited were divided into two groups,which contained 28 overlap syndrome patients and 28 patients OSAHS respectively.To compare the difference in polysomnography,pulmonary function tests and blood gas analysis.Results 1)The lowest SaO2 in the OS group were lower than that in the OSAHS group(P < 0.05).Lat,AHI in OS group were higher than those in OSAHS group(P < 0.05).2)PaCO2 in OS group were higher than that in the OSAHS group(P < 0.05) while PaO2,SO2 were lower than those in OSAHS group(P < 0.05).3)FVC%、FEV1% and FEV1/FVC% were lower than those in OSAHS group(P < 0.05).Conclusion Hypoxemia in the night in the OS group were more obvious than that in that in OSAHS group.The pulmonary function injury in the OS group were more serious than that in OSAHS group.

【关键词】 重叠综合征COPDOSAHS肺功能
【Key words】 Overlap syndromeCOPDOSAHSPulmonary function
【基金】 浙江省丽水市第二批医学重点学科科技项目(丽科[2010]57号)
  • 【文献出处】 中国现代医生 ,China Modern Doctor , 编辑部邮箱 ,2013年04期
  • 【分类号】R563.9
  • 【被引频次】10
  • 【下载频次】139
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