【摘要】 目的研究蓍草Achillea alpina地上部分的化学成分。方法利用多种柱色谱手段进行分离与纯化,通过理化性质和波谱数据鉴定化合物的结构。结果从蓍草乙醇提取物的氯仿萃取部分分离得到11个化合物,分别鉴定为表木栓醇(1)、菠菜甾醇(2)、β-谷甾醇(3)、5,6-epoxy-24(R)-methylcholesta-7,22-dien-3β-ol(4)、β-胡萝卜苷(5)、schensianol A(6)、negunfurol(7)、(3S,5S,8R)-3,5-dihydroxymegastigma-6,7-dien-9-one(8)、saropeptate(9)、(+)-丁香脂素(10)、(±)-落叶松树脂醇(11)。结论所有化合物均为首次从该植物中分离得到,其中化合物1、2、4、6~11为首次从该属植物中分离得到。更多还原

【Abstract】 Objective To investigate the chemical constituents from the aerial parts of Achillea alpina.Methods The compounds were isolated and purified by various chromatographic techniques and their structures were characterized on the basis of physicochemical properties and their spectral analyses.Results Eleven compounds were isolated.Their structures were identified as epifriedelanol(1),spinasterol(2),β-sitosterol(3),5,6-epoxy-24(R)-methylcholesta-7,22-dien-3β-ol(4),β-daucosterol(5),schensianol A(6),negunfurol(7),(3S,5S,8R)-3,5-dihydroxymegastigma-6,7-dien-9-one(8),saropeptate(9),(+)-syringaresinol(10),and(±)-lariciresinol(11).Conclusion All the compounds are isolated from the aerial parts of A.alpina for the first time,and compounds 1,2,4,6—11 are reported to obtain from the plants in Achillea L.for the first time.更多还原